全文获取类型
收费全文 | 71822篇 |
免费 | 5451篇 |
国内免费 | 872篇 |
专业分类
耳鼻咽喉 | 209篇 |
儿科学 | 2716篇 |
妇产科学 | 1000篇 |
基础医学 | 16645篇 |
口腔科学 | 462篇 |
临床医学 | 8759篇 |
内科学 | 23289篇 |
皮肤病学 | 1105篇 |
神经病学 | 1686篇 |
特种医学 | 680篇 |
外科学 | 4578篇 |
综合类 | 2494篇 |
现状与发展 | 7篇 |
一般理论 | 9篇 |
预防医学 | 8034篇 |
眼科学 | 401篇 |
药学 | 3660篇 |
17篇 | |
中国医学 | 183篇 |
肿瘤学 | 2211篇 |
出版年
2024年 | 103篇 |
2023年 | 2703篇 |
2022年 | 3516篇 |
2021年 | 4179篇 |
2020年 | 4434篇 |
2019年 | 2622篇 |
2018年 | 2879篇 |
2017年 | 2765篇 |
2016年 | 2857篇 |
2015年 | 3122篇 |
2014年 | 4830篇 |
2013年 | 3958篇 |
2012年 | 3650篇 |
2011年 | 3652篇 |
2010年 | 3482篇 |
2009年 | 3135篇 |
2008年 | 2320篇 |
2007年 | 2539篇 |
2006年 | 2342篇 |
2005年 | 2074篇 |
2004年 | 1825篇 |
2003年 | 1720篇 |
2002年 | 1713篇 |
2001年 | 1572篇 |
2000年 | 1439篇 |
1999年 | 1319篇 |
1998年 | 913篇 |
1997年 | 607篇 |
1996年 | 580篇 |
1995年 | 461篇 |
1994年 | 348篇 |
1993年 | 320篇 |
1992年 | 498篇 |
1991年 | 454篇 |
1990年 | 440篇 |
1989年 | 386篇 |
1988年 | 430篇 |
1987年 | 268篇 |
1986年 | 174篇 |
1985年 | 180篇 |
1984年 | 165篇 |
1983年 | 117篇 |
1982年 | 143篇 |
1981年 | 149篇 |
1980年 | 85篇 |
1979年 | 94篇 |
1978年 | 99篇 |
1977年 | 66篇 |
1976年 | 67篇 |
1973年 | 63篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
《Revue d'épidémiologie et de santé publique》2022,70(5):230-242
BackgroundThis systematic review aims to determine the epidemiological profile, etiology and risk factors, prevention, diagnosis, treatment, cost-effectiveness, survival, and quality of life related to cervical cancer in Morocco.MethodsThis study was conducted according to the recommendations of the "preferred reporting items for systematic reviews and meta-analysis." The PubMed, ScienceDirect, Springer, Web of Science data bases were used, as was Google Scholar for the grey literature. The review protocol was registered in the PROSPERO register (CRD42021235241).ResultsFifty studies were selected. The mean age was 49.31 ±6.3 years. HPV infection prevalence ranged from 13.30% to 76%, with a peak in HIV-positive women. Acceptability of the HPV vaccine was higher among parents (35% and 82%) than among adolescents (16.9% to 46.6%). Knowledge of the vaccine and its price are two key factors related to vaccine acceptability among parents. This systematic review highlights that the fact that few eligible women (not more than 11%) were participating in the cervical cancer screening program. Moroccan women's level of knowledge and awareness regarding cervical cancer screening was low, negatively impacting their use of such screening tools, as illustrated by the high percentage (mean 76.32% ± 17.21) of women who had never been screened for cervical cancer. Treatment was the most significant component of the global care budget (95.87%), with an annual cost of $13,027,609. Five-year overall survival ranged from 41.3% to 73.6%, with higher survival rates for patients diagnosed at an earlier stage (77.3–85% for stage I). Lastly, low quality of life was observed in women with tumors at an advanced stage who had received brachytherapy and lacked social support.ConclusionsSubjects that require further investigation include Moroccan women's knowledge, attitudes, and awareness, especially among those at high risk of developing cervical cancer, and its impact on their quality of life and survival. 相似文献
2.
3.
4.
5.
6.
《Mayo Clinic proceedings. Mayo Clinic》2019,94(7):1321-1329
Immune checkpoint inhibitors are molecules that increase the endogenous immune response against tumors. They have revolutionized the field of oncology. Since their initial approval for the treatment of advanced melanoma, their use has expanded to the treatment of several other advanced cancers. Unfortunately, immune checkpoint inhibitors have also been associated with the emergence of a new subset of autoimmune-like toxicities, known as immune-related adverse events. These toxicities differ depending on the agent, malignancy, and individual susceptibilities. Although the skin and colon are most commonly involved, any organ may be affected, including the liver, lungs, kidneys, and heart. Most of these toxicities are diagnosed by excluding other secondary infectious or inflammatory causes. Corticosteroids are commonly used for treatment of moderate and severe immune-related adverse events, although additional immunosuppressive therapy may occasionally be required. The occurrence of immune-related toxicities may require discontinuation of immunotherapy, depending on the specific toxicity and its severity. In this article, we provide a focused review to familiarize practicing clinicians with this important topic given that the use of immune checkpoint inhibitors continues to increase. 相似文献
7.
8.
9.
10.